MOTS-c

MOTS-c is a research-grade mitochondria-derived peptide (MDP) encoded within the 12S rRNA region of the mitochondrial genome. Unlike nuclear-encoded peptides, MOTS-c originates directly from mitochondrial DNA, positioning it as a key subject in research exploring the intersection of mitochondrial biology, cellular metabolism, and systemic energy regulation. At the molecular level, MOTS-c activates the AMPK (AMP-activated protein kinase) pathway, a central regulator of cellular energy homeostasis. Research applications include investigation of glucose metabolism, insulin sensitivity, mitochondrial function, and stress response pathways. Its role in modulating metabolic flexibility has also made it a subject of interest in longevity and age-related metabolic research. Available in 10mg and 40mg vials to support both small-scale and extended experimental protocols. Each batch is independently tested and supplied with a Certificate of Analysis (COA) confirming purity, identity, and concentration. For research use only. Not intended for human or veterinary use.